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Research Publications / Osteo

Repair of large osteochondral defects with allogeneic cartilaginous aggregates formed from bone marrow-derived cells using RWV bioreactor.
Yoshioka T, Mishima H, Ohyabu Y, Sakai S, Akaogi H, Ishii T, Kojima H, Tanaka J, Ochiai N, Uemura T
J Orthop Res 25:1291-1298, 2007
RhoGTPase stimulation is associated with strontium chloride treatment to counter simulated microgravity-induced changes in multipotent cell commitment.
Louis F, Bouleftour, Rattner A, Linossier MT, Vico L, Guignandon A
NPJ Microgravity. 2017 Jan 25;3:7
Strategies to Promote Chondrogenesis and Osteogenesis from Human Bone Marrow Cells and Articular Chondrocytes Encapsulated in Polysaccharide Templates
Pound JC, Green DW, Chaudhuri JB, Mann S, Roach HI, Oreffo RO
Tissue Eng 12:2789-2799, 2006
The Effect of OSM on MC3T3-E1 Osteoblastic Cells in Simulated Microgravity with Radiation
Goyden Goyden J, Tawara K, Hedeen D, Willey JS, Thom Oxford J, Jorcyk CL
PLoS One. 2015 Jun 1;10(6)
The Wnt Inhibitor Sclerostin Is Up-regulated by Mechanical Unloading in Osteocytes in Vitro
Spatz JM, Wein MN, Gooi JH, Qu Y, Garr JL, Liu S, Barry KJ, Uda Y, Lai F, Dedic C, Balcells-Camps M, Kronenberg HM, Babij P, Pajevic PD
J Biol Chem. 2015 Jul 3;290(27):16744-58
The effect of Smads signal pathway on the osteogenesis of human periodontal ligament stem cells in simulated microgravity
Li Y, Li S, Niu ZY, Bao B, Shi X
Shanghai Kou Qiang Yi Xue. 2012 Jun;21(3):246-50
The effect of simulated microgravity on human mesenchymal stem cells cultured in an osteogenic differentiation system: a bioinformatics study.
Sheyn D, Pelled G, Netanely D, Domany E, Gazit D
Tissue Eng Part A. 16(11):3403-12, 2010
The effect of simulated microgravity on osteoblasts is independent of the induction of apoptosis
Bucaro MA, Zahm AM, Risbud MV, Avyaswamy PS, Mukundakrishnan K, Steinbeck MJ, Shapiro IM, Adams CS
J Cell Biochem 102:483-495, 2007
The effects of simulated microgravity on intervertebral disc degeneration
Jin L, Feng G, Reames DL, Shimer AL, Shen FH, Li X
Spine J. 2013 Mar;13(3):235-42
Three-dimensional expansion: in suspension culture of SD rat’s osteoblasts in a rotating wall vessel bioreactor.
Song KD, Liu TQ, Li XQ, Cui ZF, Sun XY, Ma XH
Biomed Environ Sci 20:91-98, 2007
Three-dimensional simulated microgravity culture improves the proliferation and odontogenic differentiation of dental pulp stem cell in PLGA scaffolds implanted in mice.
Li Y, He L, Pan S, Zhang L, Zhang W, Yi H, Niu Y
Mol Med Rep. 2017 Feb;15(2):873-878
Treatment of hydrogen molecule abates oxidative stress and alleviates bone loss induced by modeled microgravity in rats.
Sun Y, Shuang F, Chen DM, Zhou RB
Osteoporos Int. 2013 Mar;24(3):969-78
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