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Research Publications / Osteo

3D sample preparation for orthopaedic tissue engineering bioreactors.
Cartmell SH, Rathbone S, Jones G, Hidalgo-Bastida LA
Textbook chapter in 3D Cell Culture: Methods and Protocols
A mesoscale study of the degradation of bone structural properties in modeled microgravity conditions
Cosmi F, Steimberg N, Mazzoleni G
J Mech Behav Biomed Mater. 2015 Jan 12;44C:61-70
An ex vivo model for chondrogenesis and osteogenesis
Pound JC, Green DW, Roach HI, Mann S, Oreffo RO
Biomaterials 28:2839-2849, 2007
Analysis of the attachment and differentiation of three-dimensional rotary wall vessel cultured human preosteoblasts on dental implant surfaces. Ko YJ, Zaharias RS, Seabold DA, Lafoon JE, Schneider GB Int J Oral Maxillofac Implants 25:722-728, 2010 http://www.ncbi.nlm.nih.gov/pubmed/20166753 Establishment of three-dimensional tissue-engineered bone constructs under microgravity-simulating conditions. Jin F, Zhang Y, Xuan K, He D, Deng T, Tang L, Lu W, Duan Y Artif Organs 34:118-125, 2009 http://www.ncbi.nlm.nih.gov/pubmed/20166753 NASA approved rotary bioreactor enhances proliferation and osteogenesis of human periodontal ligament stem cells. Li S, Niu Z, Qian H, Xuan D, Hou R, Ni L Stem Cells Dev. 18:1273-82, 2009 http://www.ncbi.nlm.nih.gov/pubmed/20166753 Global transcriptome analysis in mouse calvarial osteoblasts highlights sets of genes regulated by modeled microgravity and identifies a "mechanoresponsive osteoblast gene signature.
Capulli M, Rufo A, Teti A, Rucci N
J. Cell Biochem. 107:240-52, 2009
Bioreactor systems for bone tissue engineering.
Rauh J, Milan F, Gunther KP, Stiehler M
Tissue Eng Part B Rev. 2011 Aug;17(4):263-80
Bone and cartilage tissue constructs grown using human bone marrow stromal cells, silk scaffolds, and rotating bioreactors
Marolt D, Augst A, Freed LE, Vepari C, Fajardo R, Patel N, Gray M, Farley M, Kaplan D, Vunjak-Novakovic G
Biomaterials 27:6138-6149, 2006
Bone tissue engineering bioreactors: dynamic culture and the influence of shear stress.
Yeatts AB, Fisher JP
Bone; 48(2):171-81, 2011
Cell-Nanofiber based cartilage tissue engineering using improved cell seeding, growth factor and bioreactor technologies.
Li WJ, Jiang YJ, Tuan RS
Tissue Engineering: Part A. 14:639-48, 2008
Cementum protein 1 (CEMP1) induces differentiation by human periodontal ligament cells under three-dimensional culture conditions.
Hoz L, Romo E, Zeichner-David M, Sanz M, Nunez J, Gaitan L, Mercado G, Arzate H
Cell Biol Int. 2012 Feb 1;36(2):129-36
Combined Effects of Simulated Microgravity and Radiation Exposure on Osteoclast Cell Fusion.
Shanmugarajan S, Zhang Y, Moreno-Villanueva M, Clanton R, Rohde LH, Ramesh GT, Sibonga JD, Wu H
Int J Mol Sci. 2017 Nov 18;18(11)
Conditioned media from microvascular endothelial cells cultured in simulated microgravity inhibit osteoblast activity.
Cazzaniga A, Castiglioni S, Maier JA
Biomed Res Int. 2014;2014:857934
Could the effect of modeled microgravity on osteogenic differentiation of human mesenchymal stem cells be reversed by regulation of signaling pathways?
Zheng Q, Huang G, Xu Y, Guo C, Xi Y, Pan Z, Wang J
Biol Chem 388:755-763, 2007
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