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Research Publications / Liver/ Pancreas

Microgravity as a means to incorporate HepG2 aggregates in polysaccharide-protein hybrid scaffold
Sarika PR, James NR, Anilkumar PR, Raj DK, Kumary TV
J Mater Sci Mater Med. 2016; 27(2):27
Molecular mechanisms underlying the enhanced functions of three-dimensional hepatocyte aggregates
Chang TT, Hughes-Fulford M
Biomaterials. 2014; 35(7):2162-71
Preservation of glucose responsiveness in human islets maintained in a rotational cell culture system
Murray HE, Padget MB, Downing R
Mol Cell Endocrinol 2005; 238:39-49
Progressive Maturation Resistance to Microcystin-LR Cytotoxicity in Two Different Hepatospheroidal Models
Battle T, Maguire T, Moulsdale H, Doyle A
Cell Biol Toxicol 1999; 15:3-12
Proliferation Rates of HepG2 Cells Encapsulated in Alginate Are Increased in a Microgravity Environment Compared With Static Cultures
Coward SM, Selden C, Mantalaris A, Hodgson HJ
Artif Organs 2005; 29:152-158
Reconstitution of hepatic tissue architectures from fetal liver cells obtained from a three-dimensional culture with a rotating wall vessel bioreactor
Ishikawa M, Sekine K, Okamura A, Zheng YW, Ueno Y, Koike N, Tanaka J, Taniguchi H
J Biosci Bioeng. 2011
Replication of hepatitis E virus in three-dimensional cell culture
Berto A, Van der Poel WH, Hakze-van der Honing R, Martelli F, La Rogione RM, et al.
J Virol Methods. 2013; 187(2):327-32
Rotary Cell Culture System (RCCS): A New Method for Cultivation Hepatocytes on Microcarriers
Mitteregger R, Vogt G, Rossmanith E, Falkenhagen D
Int J Artif Organs 1999; 22:816-822
Rotating microgravity-bioreactor cultivation enhances the hepatic differentiation of mouse embryonic stem cells on biodegradable polymer scaffolds
Wang Y, Zhang Y, Zhang S, Peng G, Liu T, Li Y, Xiang D, Wassler MJ, Shelat HS, Geng Y
Tissue Eng Part A. 2012
Rotational Transport of Islets: The Best Way for Islets to Get around?
Oberhuber R, Mittermair C, Zelger B, Pirkebner D, Draxl A, et al.
Biomed Res Int. 2013; 2013:975608
Rotational co-culture of clonal β-cells with endothelial cells: effect of PPAR-γ agonism in vitro on insulin and VEGF secretion
Paget MB, Murray HE, Bailey CJ, Flatt PR, Downing R
Diabetes Obes Metab. 2011
Rotational culture and integration with amniotic stem cells reduce porcine islet immunoreactivity in vitro and slow xeno-rejection in a murine model of islet transplantation
Zafar A, Lee J, Yesmin S, Paget MB, Bailey CJ, Murray HE, Downing R
Xenotransplantation 2019; e12508
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