Providing Quality 3D Cell Culture Systems for
Tissue Engineering and Stem Cell Culture Applications

Neural/Neuroendocrine


The simulated microgravity enhances the differentiation of mesenchymal stem cells into neurons.

Chen J, Liu R, Yang Y, Li J, Zhang X, Li J, Wang Z, Ma J. Neurosci Lett.;505(2):171-5. Nov 2011 [abstract]

Microgravity assay of neuroblastoma: in vitro aggregation kinetics and organoid morphology correlate with MYCN expression.

Redden RA, Doolin EJ. In Vitro Cell Dev Biol Anim. 47(4):312-7, 2011 [Abstract]

Impact of Scaffold Micro and Macro Architecture on Schwann Cell Proliferation under Dynamic Conditions in a Rotating Wall Vessel Bioreactor.

Valmikinathan CM, Hoffman J, Yu X. Mater Sci Eng C Mater Biol Appl. 2011 Jan 1;31(1):22-29.[Abstract]

Effects of parabolic flight on redox status in SHSY5Y cells

Bi L, Qu LN, Huang ZM, Wang CY, Li Q, Tan YJ, Li YH. Sheng Li Xue Bao. 61: 445-50,2009 [Abstract][Full Text pdf]

Reconstruction of Functional Cortical-Like Tissues from Neural Stem and Progenitor Cells.

Ma W, Tavakoli T, Chen S, Maric D, Liu JL, O'Shaughnessy TJ.Tissue Eng Part A 14: 1687-1697, 2008 [Abstract]

Whole organ culture of the postnatal sensory inner ear in simulated microgravity.

Hahn H, Muller M, Lowenheim H. J Neurosci Methods 171: 60-71, 2008 [Abstract]

The role of connexins in the differentiation of NT2 cells in Sertoli-NT2 cell tissue constructs grown in the rotating wall bioreactor.

Shamekh R, Cameron DF, Willing AE, Saporta S:Exp Brain Res 170: 277-284, 2006. [Abstract]

Rapid Differentiation of NT2 Cells in a Sertoli-NT2 Cell Tissue Constructs Grown in the Rotating Wall Bioreactor.

Saporta S, Willing AE, Shamekh R, Bickford P, Paredes D, Cameron DF: Brain Res Bull 64: 347-356, Dec 2004 [Abstract]

Formation and Structure of Transplantable Tissue Constructs Generated in Simulated Microgravity From Sertoli Cells and Neuron Precursors.

Cameron DF, Hushen JJ, Colina L, Mallery J, Willing A, Sanberg PR, Saporta S:Cell Transplant 13: 755-763, 2004. [Abstract]

Neural Stem Cell Differentiation in a Cell-collagen-bioreactor Culture System.

Lin HJ, O’Shaughnessy TJ, Kelly J, Ma W: Develop. Brain Res 153: 163-173, 2004. [Abstract]

Effect of Culture in a Rotating Wall Bioreactor on the Physiology of Differentiated Neuron-Like PC12 and SH-SY5Y Cells.

Wang SS and Good TA:J Cell Biochem 83:574-584, 2001. [Abstract]

Neural Precursor Cells Form Rudimentary Tissue Like Structures in a Rotating-Wall Vessel Bioreactor.

Low, H.P., Savarese, T.M., and Schwartz, W.J.: In Vitro Cell Dev Biol Anim 37: 141-147, 2001. [Abstract]

Simulated Microgravity Conditions Enhance Differentiation of Cultured PC12 Cells Towards the Neuroendocrine Phenotype.
Lelkes P. et al.: InVitro Cell Dev Biol Anim 34: 316-325, 1998. [Abstract]