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Providing Quality 3D Cell Culture Systems for
Tissue Engineering and Stem Cell Culture Applications
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Cancer
Human breast cancer histoid: an in vitro 3-dimensional co-culture model that mimics breast cancer tissue.
Kaur P, Ward B, Saha B, Young L, Groshen S, Techy G, Lu Y, Atkinson R, Taylor CR, Ingram M, Imam SA. J Histochem Cytochem. 2011 Dec;59(12):1087-100 [Abstract]
Microgravity assay of neuroblastoma: in vitro aggregation kinetics and organoid morphology correlate with MYCN expression.
Redden RA, Doolin EJ. In Vitro Cell Dev Biol Anim. 47(4):312-7, 2011 [Abstract]
Generation of a tumor spheroid in a microgravity environment as a 3D model of melanoma.
Marrero B, Messina JL, Heller R. In Vitro Cell Dev Biol Anim. 45: 523-34, 2009 [Abstract]Development of a three-dimensional model of lung cancer using cultured transformed lung cells.Vertrees RA, McCarthy M, Solley T, Popov VL, Roaten J, Pauley M, Wen X, Goodwin TJ. Cancer Biol Ther 8:356-365, 2009 [Abstract]
In vitro three-dimensional modelling of human ovarian surface epithelial cells.Lawrenson K, Benjamin E, Turmaine M, Jacobs I, Gayther S, Dafou D. Cell Prolif. 42:385-93, 2009 [Abstract]
Three-dimensional in vitro cell biology models of ovarian and endometrial cancer.Grun B, Benjamin E, Sinclair J, Timms JF, Jacobs IJ, Gayther SA, Dafou D. Cell Prolif. 42:219-28, 2009 [Abstract]
Simulated microgravity decreases DNA repair capacity and induces DNA damage in human lymphocytes.Kumari R, Singh KP, Dumond JW Jr. J. Cell Biochem.107:723-31, 2009 [Abstract]
Coevolution of Prostate Cancer and Bone Stroma in Three-Dimensional Coculture: Implications for Cancer Growth and Metastasis.Sung, S-Y, Hsieh, C-L, Law A, Zhau HE, Pathak S, A Multani AS, Lim S, Coleman IM, Wu L-C, Figg WD, Dahut WL, Nelson P, Lee JK, Amin MB, Lyles R, Johnstone PAJ, Marshall FF, Chung LWK. Cancer Res 68:9996-10003, 2008 [Abstract] [Full Text] [Full Text pdf]
Characterization of primary breast carcinomas grown in three-dimensional cultures.Becker JL, Blanchard DK. J Surg Res 142: 256-262, 2007 [Abstract]
Heterogeneous breast tumoroids: An in vitro assay for investigating cellular heterogeneity and drug delivery.Vamvakidou AP, Mondrinos MJ, Petushi SP, Garcia FU, Lelkes PI, Tozeren A. J Biomol Screen 12:13-20, 2007 [Abstract]
Melanoma growth and tumorigenicity in models of microgravity.Taga M, Yamauchi K, Odle J, Furian L, Sundaresan A, Ramesh GT, Pellis NR, Andrassy RJ, Kulkarni AD. Aviat. Space Environ. Med. 77: 1113-1116, 2006 [Abstract]
Simulated Microgravity Impairs Leukemic Cell Survival Through Altering VEGFR-2/VEGF-A Signaling PathwayVincent L, Avancena P, Cheng J, Rafii S, Rabbany S; Annals of Biomedical Engineering, 33: 1405-1410, 2005 [Abstract]
Spatial Composition of Prostate Cancer Spheroids in Mixed and Static Cultures.Song H, David O, Clejan S, Giordano CL, Pappas-Lebeau H, Xu, L, O’Connor KC: Tissue Eng. 10: 7/8, 1266-1276, 2004. [Abstract]
Nitrosative stress in rotated three-dimensional colorectal carcinoma cell cultures induces microtubule depolymerization and apoptosis.Laguinge LM, Lin S, Samara RN, Salestiotis AN, Jessup JM. Cancer Res. 64: 2643-2648, 2004 [Abstract] [Full Text] [Full Text pdf]
Galectin-3 Protects Human Breast Carcinoma Cells against Nitric Oxide-Induced Apoptosis: Implication of Galectin-3 Function during Metastasis.Moon B, Lee YJ, Battle P, Jessup JM, Raz A, Kim HRC; Amer. Jour. Path. 159: 1055-1060, 2001. [Abstract] [Full Text] [Full Text pdf]
Role of Galectin-3 in Breast Cancer Metastasis: Involvement of Nitric Oxide.Song YK, Billiar TR, Lee YJ: Amer. Jour. Path. 160: 1069-1075, 2002. [Abstract] [Full Text] [Full Text pdf]
On-line Monitoring of Human Prostate Cancer Cells in a Perfusion Rotating Wall Vessel by Near-Infrared Spectroscopy.
Rhiel MH, Cohen MB, Arnold MA, Murhammer DW: Biotechnol Bioeng 86: 852-861, 2004. [Abstract]
Cytoskeletal and Functional Changes in Bioreactor Assembled Thyroid Tissue Organoids Exposed to Gamma Radiation.Green LM, Patel Z, Murray DK, Rightnar S, Burell CG, Gridley DS, Nelson GA: J Radiat. Res. 43 (supplement): S213-S218, 2002. [Abstract] [Full Text pdf]Evaluating Prostate Cancer Cell Culturing Methods: A Comparison of Cell Morphologies and Metabolic ActivityWinkenwerder JJ, Palechek PL, Reece JS, Saarinen MA, Arnold MA, Cohen MB, Murhammer DW: . Oncol.. Rep. 10: 783-789, 2003. [Abstract]
Simulated Microgravity Culture System for a 3-D CarcinomaNakamura K, Kuga H, Morisaki T, Baba E, Sato N, Mizumoto K, Sueshi K, Tanaka M, and Katano M: Tissue Model Biotechniques 33:1068-1076, 2002. [Abstract]
Characteristics of Human Dendritic Cells Generated in a Microgravity Analog Culture System In VitroSavary C, Grazziuti ML, Przepiorka D, Tomasovic SP, McIntyre BW, Woodside DG, Pellis NR, Pierson DL, Rex JH: Cell Dev Biol Anim 37:216-222, 2001. [Abstract]
Permanent Phenotypic and Genotypic Changes of Prostate Cancer Cells Cultured In a Three-Dimensional Rotating-Wall Vessel.Rhee HW, Shau HE, Pathak S, Multani AS, Oennanen S, Visakorpi T, and Chung LWK: In Vitro Cell Dev Biol Anim 37: 127-140, 2001. [Abstract]
A Novel Preclinical Model of Human Malignant Melanoma Utilizing Bioreactor Rotating-Wall Vessels.Licato LL, Prieto VG, and Grimm EA: In Vitro Cell Dev Biol Anim 37: 121-126, 2001. [Abstract]
Microgravity Culture Reduces Apoptosis and Increases the Differentiation of a Human Colorectal Carcinoma Cell LineJessup JM, Frantz M, Sonmez-Alpan E, Locker J, Skena K, Waller H, Battle P, Nachman A, Bhatti, Weber ME, Thomas DA, Curbeam RL, Baker TL, and Goodwin TJ; In Vitro Cell Dev Biol 36:367-373, 2000. [Abstract]
Biological Properties of Ulvan, a New Source of Green Seaweed Sulfated Polysaccharides, on Cultured Normal and Cancerous Colonic Epithelial Cells.Kaeffer B, Bénard C, Lahaye M, Blottiére HM, Cherbut C; Planta Med 65:6 527-531, 1999. [Abstract]
Tissue Models for the Development of Novel Anti-Cancer Therapies.O’Connor KC; Three-Dimensional Cultures of Prostatic Cells: Pharmaceutical Research 16: 486-493, 1999. [Abstract]
Three-Dimensional Culture of a Mixed Mullerian Tumor of the Ovary: Expression Of In Vivo Characteristics.Goodwin TJ, Prewett TL, Spaulding GF, Becker JL; In Vitro Cell Dev Biol Anim 33: 366-374, 1997. [Abstract]
Three-Dimensional Endothelial-Tumor Epithelial Cell Interactions in Human Cervical Cancers.
Chopra V, Dinh TV, and Hannigan EV; In Vitro Cell Dev Biol Anim 33: 432-42, 1997. [Abstract]
Three-Dimensional Growth Patterns of Various Human Tumor Cell Lines in Simulated Microgravity of a NASA Bioreactor.Ingram M, Techy GB, Saroufeem R, Yazan O, Narayan KS, Goodwin TJ and Spaulding GF; In Vitro Cell Dev Biol Anim 33: 459-466, 1997. [Abstract]Establishment of Three-Dimensional Human Prostate Organoid Coculture under Microgravity-Simulated Conditions: Evaluation of Androgen- Induced Growth and PSA Expression.Zhau HE, Goodwin TJ, Shi-Ming Chang, Baker TL and Chung LWK. In Vitro Cell Dev Bio Anim 33: 375-380, 1997. [Abstract]
Characterization of Autocrine Growth Factors, Their Receptors and Extracellular Matrix Present in Three-Dimensional Cultures of DU 145 Prostate Carcinoma Cells Grown in Simulated Microgravity.O’Connor KC, Enmon RM, Dotson RS, Primavera AC and Clejan S. Tissue Engineering 3: 161- 171 , 1997.
Induction of Carcinoembryonic Antigen Expression in a Three-Dimensional Culture System.Jessup JM, Brown D, Fitzgerald W, Ford RD, Nachman A, Goodwin TJ and Spaulding G. In Vitro Cell Dev Biol Anim 33: 352-7, 1997. [Abstract]
Cytogenetic, Morphologic and Oncogene Analysis of a Cell Line Derived from a Heterologous Mixed Mullerian Tumor of the Ovary.Becker JL, Papenhausen PR and Widen RH: In Vitro Cell Dev Biol Anim 33: 325-31, 1997. [Abstract]
Effects of Simulated Microgravity on DU 145 Human Prostate Carcinoma Cells.Clejan S, O’Conner KC, Cowger NL, Cheles MK, Haque S and Primavera AC: Biotechnol Bioeng 50: 587-597, 1996. [Abstract]
Prospects for Use of Microgravity-Based Bioreactors to Study Three Dimensional Host-Tumor Interactions in Human Neoplasia.Jessup JM, Goodwin TJ, Spaulding GF: J Cell Biochem 51: 290-300, 1993. [Abstract]
Three-Dimensional Growth and Differentiation of Ovarian Tumor Cell Line in High Aspect Rotating Wall Vessel.
Becker JL, Prewett TL, Spaulding GF, Goodwin TJ: Morphologic and Embryologic Considerations J Cell Biochem 51: 283-289, 1993. [Abstract]
Three Dimensional Modeling of T-24 Human Bladder Carcinoma Cell Line: A New Simulated Microgravity Vessel.Prewett TL, Goodwin TJ, Spaulding GF: J Tissue Culture Methods. 15: 29-36,1993. [Abstract]Morphological Differentiation of Colon Carcinoma Cell Lines HT-29 and HT-29KM in Rotating Wall Vessels.Goodwin TJ, Jessup JM, Wolf DA: In Vitro Cell Div Biol 28A:1 47-60, 1992. [Abstract]
